Modified Nucleosides and Cancer

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The elevated levels of modified nucleosides in the urine samples have served as potential cancer biomarkers in many studies. Although different analytical
Aim: We aimed at evaluation the potential diagnostic role of urinary nucleosides in urogenital tract cancer. Materials & methods: Concentrations
Modified nucleosides and deoxynucleosides are endogenous metabolites, DNA and RNA turnover is observed in various diseases, including cancer.
Thus, over- or under-represented nucleoside modifications are identified and their position Transfer RNA modification and cancer tinkering with translation.
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Unlike nucleobases, nucleoside analogs have both an aglycone and a normal or modified sugar. This group of agents contains cytarabine,
The profiles of modified nucleosides could act as useful biomarkers for cancer and cellular stress-induced diseases. However, there are no
Modified nucleosides in transfer RNA major leucine transfer ribonucleic acids (anticodon Mm-A-A) from a Morris hepatoma 5123D rat tumor.
Biochem Biophys Res Commun 89:1328 1333 Gehrke CW, Kuo KC, Waalkes TP, Borek E (1979) Patterns of urinary excretion of modified nucleosides. Cancer
The BacMam system uses a modified insect cell virus (baculovirus) as a study of virus-host interactions with a preference for viruses associated with cancers. By the use of the selective nucleoside analog ganciclovir. Were characterized: a
Background:Modified nucleosides reflect nucleic acids turnover, and are eliminated into the urine. They can serve as non-invasive biomarkers
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Transfer RNAs from normal and cancerous human breast, stomach, and colon The nucleobase-modified nucleosides in the tRNAs from cancerous breast and
This results in an increased excretion of modified nucleosides in cancer patients. Therefore, for many years modified nucleosides have been suggested as tumor
Abstract: Modified nucleoside levels in urine samples collected before and after surgery from seven patients with malignant gastrointestinal cancer were
Chemotherapeutic drugs such as gemcitabine are chemically modified nucleosides that, once incorporated into cell DNA, cause cell death.
Urinary excretion of modified nucleosides in chronic myelogenous leukemia Brief communication: Urinary excretion by cancer patients of the nucleosides N2
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This is a PDF-only article. The first page of the PDF of this article appears above. PreviousNext. Back to top. May 1982. Volume 42, Issue 5. Table of Contents



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